Generate High- Quality Evidence For Pediatric Trials

Pediatric clinical trials present unique challenges that require specialized expertise, tailored methodologies, and adaptable technology solutions. High placebo response rates, COA selection  & versioning, and the need for age-appropriate trial designs all complicate the generation of reliable evidence. Signant Health addresses these complexities through an integrated approach that combines scientific consulting, innovative technology, and operational expertise.

Our clinical and scientific teams guide sponsors in selecting appropriate clinical outcome assessments, advising when self-report, proxy, or observer versions are most suitable, and enabling seamless in-trial transitions between age-related measures. With experience in over 190 pediatric studies across more than 60 indications, Signant combines technology and deep therapeutic knowledge to support regulatory alignment, optimize site performance, and deliver reliable outcomes. These solutions enable sponsors to generate the high-quality data required to advance safe and effective therapies for children.