Articles by Rachel Grabenhofer

  1. Can Your Operating Model Grow? Preparing Clinical Supply For What Comes Next 8/10/2026

    Having previously explained why early-stage biotechs should avoid overbuilding, Alicia Collins, of Tune Therapeutics, continues the discussion here in part 2, with thoughts on scaling clinical supply, selecting partners, and preparing for future constraints.

  2. The Biggest Early-Stage Clinical Supply Mistake? Building Too Much, Too Soon. 8/3/2026

    Early-stage biotechs often overbuild systems too soon. Alicia Collins explains why flexibility, simple processes, and realistic assumptions matter most.

  3. How Clinical Supply Is Shaping The Next Generation Of Cell And Gene Therapies 7/31/2026

    From CAR-T to gene editing, clinical supply realities are increasingly influencing therapeutic design, scalability, and patient access.

  4. First Advisors In: Meet Clinical Supply Leader's Inaugural Board Members 7/16/2026

    Clinical Supply Leader unveils its first Editorial Advisory Board, featuring leaders across clinical supply, quality, regulatory affairs, technology, and strategy.

  5. What Clinical Wishes Supply Did Better – And How To Close The Gap: Part 3 – Staying Aligned in a Moving System 6/23/2026

    Even strong plans fail without real-time alignment. As trials evolve, shared visibility, coordinated response, and early supply involvement keep execution on track.

  6. What Clinical Wishes Supply Did Better – And How To Close The Gap: Part 2 – Where Assumptions Break Trials 6/16/2026

    Even strong plans fail without real-time alignment. As trials evolve, shared visibility, coordinated response, and early supply involvement keep execution on track.

  7. What Clinical Wishes Supply Did Better – And How To Close The Gap: Part 1 – The Cost Of Late Involvement 6/9/2026

    Late involvement turns small gaps into costly problems. Bringing clinical supply in early improves planning, communication, and prevents downstream issues.

  8. Invisible Yet Accountable: How Clinical Supply Pressures Build Strategic Leaders 6/1/2026

    Clinical supply leaders operate under unseen pressure, balancing risk, uncertainty, and tradeoffs — building strategic judgment that drives trial success.

  9. From Invisible to Integral: Inviting Clinical Supply Expertise to the Planning Table 6/1/2026

    Clinical supply leaders bring resilience, adaptability, and judgment; integrating their expertise early in planning strengthens trial execution and strategic decision-making.

  10. Decision Authority And Direction — The Gap In Deviation Planning 5/27/2026

    Faster excursion detection improves supply visibility but also exposes an often-overlooked gap: a deviation plan outlining who has authority and what actions to take.