Articles by John O'Brien

1. The Fifth Model: Where It Works, Where It Doesn't, And The Economics Behind It 7/21/2026

   Where does the pharmacy card model fit? Explore its operational limits, cost advantages, regulatory considerations, and impact on comparator supply strategy.

2. Beyond Push: A Pull-Based Model For Comparator Supply 7/14/2026

   A prescription-based comparator supply model replaces bulk forecasting with on-demand dispensing, reducing lead times, waste, and inventory while expanding patient access.

3. Zen And The Art Of Comparator Supply Maintenance 5/26/2026

   Comparator sourcing may be the most expensive blind spot in clinical trials, driving massive waste, delays, shortages, and operational risk.